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Proper bowel cleansing before colonoscopy is an important factor to increase the detection rate of lesions. Low volume polyethylene glycol (PEG) plus ascorbic (PEG-Asc) has reduced the dosage of previous bowel preparation agent, but it still presents discomfort to patients. The aim of this study was to confirm the efficacy and convenience of volume reduction of PEG-Asc by adding bisacodyl suppository at the same day by compared with conventional 2L PEG-Asc.
Eligibility criteria: outpatients between the ages of 20 and 70 years, who were scheduled for colonoscopy between August 2017 and January 2018
Exclusion criteria: patients with a history of gastrointestinal tract surgery, inflammatory bowel disease, severe active colitis, underlying chronic kidney disease, or pregnancy.
Outcome measures: the Boston Bowel Preparation Scale (BBPS)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 2L PEG-Asc | Experimental | 2L PEG-Asc for bowel preparation |
|
| 1L PEG-Asc & 'Bisacodyl 10Mg Suppository | Active Comparator | 1L PEG-Asc with 'Bisacodyl 10Mg Suppository for bowel preparation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 2L PEG-Asc | Drug | PEG-Asc powder |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Boston Bowel Preparation Scale (BBPS). | 4-point scoring system (0-3) applied to each of the 3 colon segments (right colon including cecum and ascending colon, transverse colon including transverse colon, hepatic and splenic flexure, left colon including descending colon, sigmoid colon, and rectum) | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| brian.biochem@gmail.com Kim | Samsung Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung Medical Center | Seoul | 06351 | South Korea |
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| ID | Term |
|---|---|
| D001726 | Bisacodyl |
| D013488 | Suppositories |
| ID | Term |
|---|---|
| D003408 | Cresols |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
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prospective, randomized, and observer-blind study
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| Bisacodyl 10Mg Suppository | Drug | bisacodyl 10 mg suppository |
|
| 1L PEG-Asc | Drug | PEG-Asc powder |
|
|
| D006844 |
| Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
| D004304 | Dosage Forms |
| D004364 | Pharmaceutical Preparations |