Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in At-risk Patients

Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in

One-step exchange arthroplasty is more and more used in the treatment of chronic infections, especially in patients at risk anesthetic.

This strategy is not recommended in patients infected with multidrug-resistant organisms or difficult to treat because of a risk of bacterial persistence on the new implant.

Antibiotic pretreatment by a narrow-spectrum molecule and for which resistance acquisition is difficult might be of interest to try to reduce the inoculum and avoid contamination of the new implant.

Inclusion Criteria:

• patients having had a antibiotic pretreatment targeted before a one step exchange arthroplasty

Exclusion Criteria:

• none