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This study concerns patients having had an infection on their prosthesis (hip, knee,..) and for whom a 2-step exchange of prosthesis has been done.
A 2-step exchange consists in explantation of the prosthesis and implementation of a spacer at the first stage, and reimplantation of a new prosthesis in a second stage. Patients with late prosthetic joint infection are at risk for superinfection at the time of reimplantation.
The aim is to determine the microbiological epidemiology in patients experiencing failure following reimplantation to establish, based on the drug susceptibilities, which cement could be the most active.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| failure after reimplantation | description of the failure at the reimplantation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| failure after reimplantation | Other | description of cinical and microbiological failure |
|
| Measure | Description | Time Frame |
|---|---|---|
| rate of treatment failure | Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption) |
| Measure | Description | Time Frame |
|---|---|---|
| rate of bacteria involved in microbiological failure | description of microbiological failure : bacteria responsible of microbiological failure | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption) |
| rate of clinical failure |
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Inclusion Criteria:
Exclusion Criteria:
-
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patients with prosthetic joint infection having had a 2-step exchange managed at the Croix Rousse Hospital from the reimplantation, between 2013 and 2015.
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| Name | Affiliation | Role |
|---|---|---|
| Tristan FERRY, Md,PhD | Hospices Civils de Lyon Hôpital de la Croix-Rousse | Principal Investigator |
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description of clinical failure |
| Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption) |
| ID | Term |
|---|---|
| D001424 | Bacterial Infections |
| ID | Term |
|---|---|
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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