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| Name | Class |
|---|---|
| University of Cincinnati | OTHER |
| The Cleveland Clinic | OTHER |
| University Health Network, Toronto | OTHER |
| University of Michigan |
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Investigators have developed a comprehensive questionnaire that assesses the presence of non-motor fluctuations (NMFs) in individuals with Parkinson's disease (PD). To date, 189 participants with PD have been assessed for preliminary data analysis prior to developing the penultimate version. At this time the objectives are to: (i) assess the scale's internal consistency and item-to-total correlations; (ii) assess test-retest reliability; (iii) use factor analysis and reliability measures to guide item reduction; (iv) assess construct validity; and (v) assess the scales ability to discriminate between static non-motor symptoms and non-motor symptoms which fluctuate (vi) estimate the relative distribution of cognitive, psychiatric, autonomic, sleep and sensory NMFs in PD patients with motor fluctuations and their impact on quality of life in Parkinson's disease.
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| Measure | Description | Time Frame |
|---|---|---|
| Cronbach's Alpha | alpha 0 - 1.0 | Baseline |
| Item-to-total correlation | correlation -1.0 - 1.0 | Baseline |
| Inter-rater reliability | kappa 0 - 1.0 | 1 week after Baseline |
| Concurrent validity | correlation -1.0 - 1.0 | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Individuals, both men and women, who have been diagnosed with idiopathic Parkinson's Disease and have motor and non-motor fluctuating symptoms are invited to participate in the study. To ensure a representative sample, subjects spanning the disease spectrum will be equally represented in terms of mild, moderate and advanced symptoms of PD.
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| Name | Affiliation | Role |
|---|---|---|
| Galit Kleiner, MD | Assistive Technology Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assistive Technology Clinic | Toronto | Ontario | M6A 2E1 | Canada |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| OTHER |
| Rush University | OTHER |
| The Parkinson Study Group | NETWORK |
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| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |