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This retrospective study aims to investigate pregnancy outcome in women with heterozygous hemoglobinopathies (regarding gestational diabetes, cholestasis and urinary tract infections) and to analyze if there are aggravated maternal and/or perinatal risks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Heterozygous Hemoglobinopathy | pregnancy outcome in women with heterozygous hemoglobinopathy |
| |
| No Heterozygous Hemoglobinopathy | pregnancy outcome in women without heterozygous hemoglobinopathy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pregnancy outcome | Other | descriptive statistics of variables |
|
| Measure | Description | Time Frame |
|---|---|---|
| gestational diabetes | number of women developing gestational diabetes in pregnancy | in the course of pregnancy until delivery |
| cholestasis in pregnancy | number of women developing cholestasis in pregnancy | in the course of pregnancy until delivery |
| urinary tract infection | number of women developing urinary tract infection | in the course of pregnancy until delivery |
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Inclusion Criteria:
Exclusion Criteria:
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pregnant women being treated at Universitätsspital Basel/ Frauenklinik (from 2015 until 2017) and at Universitätsspital Zürich (from 2004-2006)
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| Name | Affiliation | Role |
|---|---|---|
| Irene Hoesli, Prof. Dr. MD | Frauenklinik Universitätsspital Basel | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Frauenklinik University Hospital Basel | Basel | 4031 | Switzerland | |||
| Frauenklinik University Hospital Zürich |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33842991 | Result | Kasparek J, Burkhardt T, Hoesli I, Amstad Bencaiova G. Pregnancy outcomes in women with a hemoglobinopathy trait: a multicenter, retrospective study. Arch Gynecol Obstet. 2021 Nov;304(5):1197-1203. doi: 10.1007/s00404-021-06058-y. Epub 2021 Apr 11. |
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| ID | Term |
|---|---|
| D016640 | Diabetes, Gestational |
| ID | Term |
|---|---|
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D003920 | Diabetes Mellitus |
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| ID | Term |
|---|---|
| D011256 | Pregnancy Outcome |
| ID | Term |
|---|---|
| D011379 | Prognosis |
| D003933 | Diagnosis |
| D011247 | Pregnancy |
| D012098 | Reproduction |
| D055703 |
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| Zurich |
| 8091 |
| Switzerland |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| Reproductive Physiological Phenomena |
| D012101 | Reproductive and Urinary Physiological Phenomena |