The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section

The Phenylephrine vs. Norepinephrine Infusion by Lidico Monitoring With Pregnancy Patients Undergoing Cesarean Section

Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine effect on fetus and parturient during Cesarean Section

1. Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine and control group effect on parturient hemodynamic change (systolic blood pressure SBP, diastolic blood pressure DBP,mean arterial pressure MAP,heart rate HR) and on LIDICO-rapid monitoring ( stroke volume SV, systemic vascular resistance SVR, cardiac output CO) and peripheral vein (PV) blood gas during Cesarean Section.
2. Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine and control group effect on fetus by blood gas of the umbilical vein (UV), umbilical artery (UA),

Inclusion Criteria:

• a healthy singleton pregnancy scheduled for elective cesarean delivery (CD) under combined spinal-epidural anesthesia (CSEA),
• American Society of Anesthesiologists (ASA) physical status I/II
• 20 to 40 years old

Exclusion Criteria:

• history of mental disorder or epilepsy,
• tricyclic or imipramine antidepressant use,
• central nervous system (CNS) disease,
• preexisting or pregnancy-induced hypertension,
• lumbar injury,
• severe hypovolemia,
• allergy
• history of hypersensitivity to vasopressor
• body mass index (BMI) >40 kg/m2,
• infection at the puncture site