Gabapentin Pretreatment for Staged Bilateral Cataract Operations

The Effect of Gabapentin Pretreatment on Hyperalgesia in Elderly Patients Undergoing Staged Bilateral Cataract Operations

To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care

It has been reported that patients with bilateral cataract complained more pain and discomfort during the second consecutive eye surgery compared to the first eye surgery.

Gabapentin is an anticonvulsant drug, which has been extended the use to perioperative analgesia, and anxiolysis.

Therefore, the investigators conducted this randomized, controlled study to evaluate the effects of gabapentin premedication on patients' subjective sensations, including intraoperative anxiety, perceptions of pain, and light sensitivity, in the second cataract operations.

Inclusion Criteria:

• patients aged over 60 years, who undergoing staged bilateral cataract operations under monitored anesthesia care
• ASA physical status of I, II, and III

Exclusion Criteria:

• undergoing other eye operations together besides cataract operation
• patients with creatinin clearance lower than 30ml/min
• patients with CNS inhibitors medication
• patients with previous gabapentin medication
• pregnancy