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To investigate which treatment option (corticosteroid treatment alone or combined corticosteroid treatment and vestibular rehabilitation) is the most effective in patients diagnosed with vestibular neuritis.
Patients diagnosed with vestibular neuritis will we consider for enrollment. Each patient will undergo randomization for a specific treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Neuritis vestibularis (group 1) | Active Comparator | Corticosteroid ("prednisolone") |
|
| Neuritis vestibularis (group 2) | Experimental | Corticosteroid ("prednisolone") + vestibular rehabilitation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vestibular rehabilitation | Other | Specialized physical therapy aimed at restoring balance |
|
| Measure | Description | Time Frame |
|---|---|---|
| Suppressing head impulse paradigm (SHIMP) | SHIMP equipment will objectively quantify change of vestibular function. | 6 month |
| Subjective visual vertical (SVV) | SVV test will objectively quantify the experienced spatial orientation as an indicator of visual and vestibular otolithic function | 6 month |
| Video head impulse test (v-HIT) | v-HIT equipment will objectively quantify change of vestibular function. | 6 month |
| Dizziness handicap inventory (DHI) questionnaire | Fulfillment of the questionnaire "Dizziness Handicap Inventory" (DHI) will quantify the level of experienced vertigo. | 6 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dan D Hougaard, MD | Aalborg University Hospital | Principal Investigator |
| Martin H Wolder, MS | Aalborg University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Otolaryngology, Head & Neck Surgery and Audiology | Aalborg | North Denmark | 9000 | Denmark |
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| ID | Term |
|---|---|
| D020338 | Vestibular Neuronitis |
| ID | Term |
|---|---|
| D000160 | Vestibulocochlear Nerve Diseases |
| D012181 | Retrocochlear Diseases |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
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| ID | Term |
|---|---|
| D000305 | Adrenal Cortex Hormones |
| ID | Term |
|---|---|
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |
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Patients randomized to two different treatments:
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| Corticosteroid | Drug | Prednisolone |
|
| D003389 | Cranial Nerve Diseases |
| D009422 | Nervous System Diseases |