Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation

The Effect of Continuous Propofol Versus Dexmedetomidine Infusion on Regional Cerebral Tissue Oxygen Saturation During Cardiopulmonary Bypass

50 patients divided into 2 groups

.Group I Dexmedetomidine infusion. Group II with Propofol infusion

: 50 patients anticipated for open heart surgeries were encompassed in the study. Patients were divided into 2 groups, group P (receiving propofol) and group D (receiving dexmedetomidine) during CPB. Both groups were studied for variations in right and left rScO2 as well as postoperative cognitive dysfunction using the Mini Mental State Examination Score (MMSE) test.

Inclusion Criteria:

• Patients undergoing valve surgeries
• Patients undergoing on pump coronary artery bypass grafting surgeries

Exclusion Criteria:

• emergency cases, patients with cervical spine pathology (cervical stenosis, cervical disc herniation, carotid stenosis), patients with cerebral pathology (cerebral strokes, ischemic attacks), patients with Mini Mental State Examination Score (MMSE) of 23 or less, complicated cases with prolongation of the cardiopulmonary bypass period, patients needing moderate hypothermia