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To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.
Two groups each with 60 patients Group I anesthesia initiated by propofol, fentanyl and cisatracurium. Group II anesthesia initiated by ketamine, lidocaine, propofol and cisatracurium.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fentanyl | Active Comparator | Administered propofol and fentanyl for induction. |
|
| Ketamine and lidocaine | Active Comparator | Administered propofol, ketamine and lidocaine for induction. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ketamine | Drug | ketamine |
| |
| Propofol |
| Measure | Description | Time Frame |
|---|---|---|
| Intubation with less hemodynamic changes | changes in blood pressure with intubation | 15 minutes after induction of anesthesia. |
| Smooth Maintenance of anesthesia | changes in blood pressure during anesthesia | anesthesia time |
| less postoperative pain killers | amount of pain killers used and timing | 24 hours postoperative |
| Intubation with less hemodynamic changes | changes in pulse rate during anesthesia | Anesthesia time |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams University hospitals | Cairo | Egypt |
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| ID | Term |
|---|---|
| D007649 | Ketamine |
| D015742 | Propofol |
| D005283 | Fentanyl |
| C101584 | cisatracurium |
| D008012 | Lidocaine |
| ID | Term |
|---|---|
| D003510 | Cyclohexanes |
| D003516 | Cycloparaffins |
| D006840 | Hydrocarbons, Alicyclic |
| D006844 | Hydrocarbons, Cyclic |
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| Drug |
propofol |
|
| Fentanyl | Drug | fentanyl |
|
| Cisatracurium | Drug | cisatracurium |
|
| Lidocaine | Drug | lidocaine |
|
| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D000814 | Aniline Compounds |
| D000588 | Amines |