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The study is to translate the Medical, Epidemiologic, and Social aspects of Aging (MESA) urinary incontinence questionnaire into a Chinese language version and test the reliability and validity among women with urgency-predominant mixed urinary incontinence.
The hypothesis is that the Chinese language version of the MESA questionnaire will have adequate measurement properties (e.g. reliability and validity).
Mixed urinary incontinence(MUI) is regarded as urgency-predominant when urgency incontinence episodes dominate over stress incontinence episodes, and vice versa. The treatment of MUI often begins with the most bothersome symptoms.
MESA questionnaire is a reliable and validated tool to evaluate the severity and predominance of stress or urgency urinary incontinence. At present, it hasn't been translated into a Chinese language version and validated.
The validation study of MESA questionnaire is embedded in a randomized controlled trial conducted among female patients, of which the data will be collected and analysed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Group 1 is anticipated to consist of 300 women with MUI, and the categorization function of MESA questionnaire will be validated among those patients. | ||
| Group 2 | Group 2 is anticipated to consist of 282 women with urgency-predominant MUI. | ||
| Group 3 | Group 3 is anticipated to consist of 94 women with urgency-predominant MUI. |
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| Measure | Description | Time Frame |
|---|---|---|
| The criteria validity of MESA questionnaire compared with extended clinical evaluation in deciding predominant components of MUI. | The extended clinical evaluation mainly includes physical examination, 3-day voiding diary, cough stress teat, urinalysis and residual urine volume by ultrasonography. | screening and baseline periods |
| Measure | Description | Time Frame |
|---|---|---|
| The criteria validity of MESA questionnaire compared with International Consultation on Incontinence Questionnaire Short Form (ICIQ SF) in severity assessing among women with urgency-predominant mixed urinary incontinence. | ICIQ SF is a validated questionnaire to evaluate both the severity of incontinence symptoms and influence on QoL in the past four weeks. The questionnaire is consisted of four items, including frequency, leakage amount, impact on QoL and the cause of urinary incontinence. The total score of the ICIQ SF ranges from 0 to 21, with a higher score indicating worse symptoms and QoL. |
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Inclusion criteria
For patients in group 2 and groups 3, all inclusion criteria are required to meet.
Exclusion criteria
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The questionnaire validation is targeted at women with urgency-predominant mixed urinary incontinence.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhishun Liu, PhD | Contact | 86-010-88002331 | zhishunjournal@163.com | |
| Yuanjie Sun, Master | Contact | 86-010-18810337542 | puzhisun@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Zhishun Liu, PhD | Guang An Men Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guang An Men Hospital | Recruiting | Beijing | 100053 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31689809 | Derived | Sun Y, Liu Y, Su T, Yuan J, Liu Z. Medical, epidemiologic, and social aspects of aging urinary incontinence questionnaire: Study protocol for the translation and validation of a Chinese language version. Medicine (Baltimore). 2019 Nov;98(44):e17719. doi: 10.1097/MD.0000000000017719. |
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| baseline |
| The criteria validity of MESA questionnaire compared with 3-day voiding diary in severity assessing among women with urgency-predominant mixed urinary incontinence. | In 3-day voiding diary, the type and episodes of incontinence are all recorded. | baseline |
| The test-retest reliability of MESA questionnaire | The test-retest reliability of MESA will be evaluated at the screening and baseline period with about one- to two-week interval among women with urgency-predominant mixed urinary incontinence. | screening and baseline periods |
| The responsiveness of MESA questionnaire | The responsiveness of MESA questionnaire will be evaluated before and after the treatment among women with urgency-predominant mixed urinary incontinence compared with 3-day voiding diary and ICIQ SF. | baseline, week 12 |