A better suture technology will reduce postoperative incision complications. This study is designed to compare mass continous suture with PDS and interrupted suture with thread on major abdominal incision.

A better suture technology will reduce postoperative incision complications. The previous retrospective cohort study from the investigator has demonstrated that continuous mass suture with PDS led to shorter incision closure time, early wound healing and comparable incisional complications versus interrupted thread suture. As such, the current RCT study will include 100 subjects with major abdominal incision. They will be divided into two groups randomly: Mass suture gorup, mass continuous suture with PDS, Control group, interrupted suture with thread. The wound healing time, stitches removal time and incidence of incision complications will be compared between the two groups.

Inclusion Criteria:

• the patient with major abdominal incision.
• the incision is longer than 10 cm
• aged between 18 to 65 years old

Exclusion Criteria:

• Pregnant woman
• Patient with diabetes
• Patient with a history of cardiovascular disease, including coronary heart disease and stroke.
• Severe lung diseases such as COPD and asthma
• Patients undergoing emergent or infectious surgery
• Patients with surgical site infection
• No autonomy, inability or unwillingness to participate in follow-up