the Prevalence of "Wearing-off" in Patients With Parkinson's Disease in Shanghai

the Prevalence of "Wearing-off" in Patients With Parkinson's Disease in Shanghai, China: a Cross-sectional Investigation

The study would be designed as a multi-center cross-sectional investigation on the prevalence of Wearing-off in Parkinson's patients in Shanghai as well as related influencing factors.

PD patients would be randomly recruited into this investigation from around thirty hospital covering the 16 districts of Shanghai. The wearing off would be defined by two methods: the doctors' judgement or the WOQ-9 questionnaire which was a patient-determining tool. The investigation also includes the medicine, the severity of PD symptoms, the demographic factors. The study would be designed with the purpose of clarifying the prevalence of the "wearing-off" and its related influencing factors.

Inclusion Criteria:

• have been clinical diagnosed with Parkinson's disease
• have received stable anti-Parkinson's treatment before being recruited to the study.

Exclusion Criteria:

• being suspicious of atypical Parkinson syndrome or secondary Parkinson syndromes
• have not received anti Parkinsonian treatment.
• being combined with serious cognitive dysfunction or psychiatric symptoms
• unable to complete the investigations.