Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review
Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review
The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs.
Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.
Inclusion Criteria:
recurrent urinary tract infections (RUTIs)
Exclusion Criteria:
Upper urinary tract infections, severe clinical symptoms, fever > 37,5 with lumbar pain