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Effect of Some Drugs on Liver Fibrosis
The study aimed at evaluating the effect of Some Drugs on Liver Fibrosis
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | No Intervention | No intervention | |
| Candesartan | Active Comparator | Candesartan 8 mg/day |
|
| Ramipril | Active Comparator | Ramipril 1.25 mg/day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Candesartan | Drug | Candesartan 8 mg/day |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Fibroscan or APRI score | Change in Fibroscan or APRI score | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sherief Abd-Elsalam, Ph D | Contact | 00201147773440 | sheriefabdelsalam@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Gamal El-azab, Prof | Clinical pharmacy Department- Tanta University | Principal Investigator |
| Tarek Mostafa, Prof | Cardiology Department- Tanta University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sherief Abd-Elsalam | Recruiting | Tanta | 35111 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34925649 | Derived | Mostafa TM, El-Azab GA, Badra GA, Abdelwahed AS, Elsayed AA. Effect of Candesartan and Ramipril on Liver Fibrosis in Patients with Chronic Hepatitis C Viral Infection: A Randomized Controlled Prospective Study. Curr Ther Res Clin Exp. 2021 Nov 12;95:100654. doi: 10.1016/j.curtheres.2021.100654. eCollection 2021. |
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| ID | Term |
|---|---|
| D008103 | Liver Cirrhosis |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D005355 | Fibrosis |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| C081643 | candesartan |
| D017257 | Ramipril |
| ID | Term |
|---|---|
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
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| Ramipril | Drug | ramipril 1.25 mg/day |
|
| Gamal Badra, Prof |
| National Hepatology Institute - Egypt |
| Study Chair |
| Abeer El-Motwally, Msc | Clinical pharmacy Department-Tanta University | Study Chair |
| D013568 |
| Pathological Conditions, Signs and Symptoms |