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The aim of this study is to determine whether ALDH2 gene polymorphisms (G/G, G/A A/A) have effect on the potency of propofol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| G/G group | Patients who are determined to be G/G genotype. |
| |
| G/A A/A group | Patients who are determined to be G/A or A/A genotypes. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Propofol | Drug | Patients will be induced to unconsciousness using propofol intravenously. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Effect-site concentration | patient's effect-site concentration when he/she loss consciousness | immediately after patient lose his/her consciousness |
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Inclusion Criteria:
Exclusion Criteria:
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operation rooms for cardiac surgeries in our institution（a major hospital in China)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kefang Guo, MD | Contact | +86-13817706936 | drguokefang@foxmail.com |
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| ID | Term |
|---|---|
| D015742 | Propofol |
| ID | Term |
|---|---|
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
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| D006838 |
| Hydrocarbons |
| D009930 | Organic Chemicals |