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study the cutaneous expression of PGF2α in vitiligo patients and compare it with normal control subjects.
Measurement of tissue levels of PGF2α in vitiligo patients and compare them with healthy controls.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| vitiligo patients | Active Comparator | Two skin biopsies (lesional and non-lesional) will be taken from every patient. |
|
| healthy controls | Experimental | A skin biopsy will be taken from each control subject. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Skin biopsy | Other | Two skin biopsies (lesional and non-lesional) will be taken from every patient. Also a skin biopsy will be taken from each control subject. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of tissue levels of PGF2α in vitiligo patients and compare them with healthy controls. | Measurement of tissue levels of PGF2α in vitiligo patients and compare them with healthy controls to study and verify the hypothesis of involvement of PGF2α in the pathogenesis of vitiligo.• Skin biopsy for assessment of tissue levels of the PGF2α will be taken from both lesional and non lesional skin of patients of vitiligo and from normal skin of healthy controls. All skin biopsies are from non-sun exposed sites. | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D014820 | Vitiligo |
| ID | Term |
|---|---|
| D017496 | Hypopigmentation |
| D010859 | Pigmentation Disorders |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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