Amblyopia is treated by glasses and patches or blurring eyedrops to the good eye. This works in about 70% of children, but parents and children strongly dislike these treatments which may carry on for years and involve frequent clinic visits. In this pilot trial, 66 children will receive, at random, either a Nintendo 3DSXL console with movies, or standard patching/blurring eye-drop treatment. The Investigators will monitor adverse events (double vision), change in the balance between the two eyes and in visual acuity over 16 weeks.

"Lazy eye" (amblyopia) is the commonest sight problem in children, affecting about one in 30 children. It is caused by a difference in spectacle prescription between the eyes and/or a squint (eye misalignment), with the brain ignoring one eye. Amblyopia is treated by glasses and patches or blurring eyedrops to the good eye. This works in about 70% of children, but parents and children strongly dislike these treatments which may carry on for years and involve frequent clinic visits.

The Investigators have developed an exciting new treatment: children watch customized movies for an hour a day on a hand-held 3D computer-game console. The Investigators blur the picture that the good eye sees to match it with what the weaker eye sees. They have tested this approach on 22 children, with an average improvement in vision by three lines on the test chart over 8 - 24 weeks, which may be faster than with standard treatment. Parents and children the Investigators have spoken with like both the idea of research in this area and the engaging nature of this device. The Investigators now need to assess how the new treatment compares with standard treatment, but first need to ensure that the new treatment is safe and that families will use it.

In this pilot trial, 66 children will receive, at random, either a Nintendo 3DSXL console with movies, or standard patching/blurring eye-drop treatment. The Investigators will monitor adverse events (double vision), change in the balance between the two eyes and in visual acuity over 16 weeks. Parents and children have helped develop this pilot - this involvement will be continued throughout the study. At study completion, children and parents will be involved in deciding how best to communicate the findings on hospital websites, in newsletters, at conferences and in medical journals.

Inclusion Criteria:

• Age between 3.0 and less than 8.0 years
• unilateral anisometropic, strabismic or combined mechanism amblyopia
• best-corrected crowded logMAR visual acuity (BCVA) in the amblyopic eye worse than 0.2logMar
• best corrected visual acuity in the better seeing eye 0.2 or better
• difference in best corrected visual acuity between the two eyes of 0.2 logMAR or more
• adapted to spectacles with no improvement in acuity in affected eye for two consecutive visits
• no previous treatment for amblyopia other than glasses

Exclusion Criteria:

• ocular cause for reduced visual acuity
• inability to co-operate with assessment tests
• other developmental disorders or learning or neurological disability that would impact on adherence to treatment
• photopic epilepsy
• myopia with spherical equivalent of greater than -6.00DS
• previous intraocular surgery
• inability to perform a crowded letter logMAR visual acuity test using a clinical trials standard testing method (ATS-HOTV protocol), either by naming or by matching letters

Individual-level data will be made available on request to the principal investigator.

Will be made available after publication of the trial findings.

As per review by sponsor and principal investigator.

At each site, a masked orthoptist will carry out the study assessments.