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| Name | Class |
|---|---|
| Wellcome Trust | OTHER |
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The study aims to determine whether 30 minutes of treatment playing an interactive computer game weekly for 6 weeks, improves visual acuity. The game has been specially configured to ensure the amblyopic eye is preferentially stimulated and the patient wears shutter glasses which manipulate the image seen by each eye in order to provide more information to the amblyopic eye. Patients will be randomised to play the computer game using the I-BiTTM technology, play the computer game but without the I-BiTTM technology, or watch a DVD using the I-BiTTM technology.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| I-BiTTM game | Experimental | 30 minutes intervention weekly for 6 weeks. |
|
| Non-I-BiTTM game | Active Comparator | 30 minutes intervention weekly for 6 weeks. |
|
| I-BiTTM DVD | Experimental | 30 minutes intervention weekly for 6 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| I-BiTTM game | Device | 30 minutes intervention weekly for 6 weeks. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in visual acuity | 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in visual acuity | 10 weeks |
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Inclusion criteria:
Exclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alexander Foss, BA BMBCh MRCP MRCOphth FRC | Consultant Ophthalmologist | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cambridge University Hospitals NHS Trust | Cambridge | Cambridgeshire | CB2 0QQ | United Kingdom | ||
| Nottingham University Hospitals NHS Trust |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35129211 | Derived | Tailor V, Ludden S, Bossi M, Bunce C, Greenwood JA, Dahlmann-Noor A. Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years. Cochrane Database Syst Rev. 2022 Feb 7;2(2):CD011347. doi: 10.1002/14651858.CD011347.pub3. | |
| 26951772 | Derived | Herbison N, MacKeith D, Vivian A, Purdy J, Fakis A, Ash IM, Cobb SV, Eastgate RM, Haworth SM, Gregson RM, Foss AJ. Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system. Br J Ophthalmol. 2016 Nov;100(11):1511-1516. doi: 10.1136/bjophthalmol-2015-307798. Epub 2016 Mar 7. |
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| ID | Term |
|---|---|
| D000550 | Amblyopia |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014786 | Vision Disorders |
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| Non-I-BiTTM game |
| Device |
30 minutes intervention weekly for 6 weeks. |
|
| I-BiTTM DVD | Device | 30 minutes intervention weekly for 6 weeks. |
|
| Nottingham |
| Nottinghamshire |
| NG7 2UH |
| United Kingdom |
| 23688108 | Derived | Foss AJ, Gregson RM, MacKeith D, Herbison N, Ash IM, Cobb SV, Eastgate RM, Hepburn T, Vivian A, Moore D, Haworth SM; I-BiT Steering group. Evaluation and development of a novel binocular treatment (I-BiT) system using video clips and interactive games to improve vision in children with amblyopia ('lazy eye'): study protocol for a randomised controlled trial. Trials. 2013 May 20;14:145. doi: 10.1186/1745-6215-14-145. |
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D005128 | Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |