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Regional tissue oxygenation saturation has been shown to increase in innervated regions after sympathetic block. The aim of this prospective observational study was to evaluate the changes of regional tissue oxygenation saturation by near-infrared spectroscopy after successful femoral nerve block with ropivacaine and determine whether the changes of regional tissue oxygenation saturation can be affected by the concentration of ropivacaine.
Successful peripheral nerve blocks induce sympathetic blockade, which increases local blood flow by vasodilation. The relationship between successful femoral nerve block and the variation of regional tissue oxygenation saturation was unclear.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| H group | Patients scheduled for elective knee arthroscopy with peripheral nerve block will receive ultrasound-guided femoral nerve block with 0.5% ropivacaine. Regional tissue oxygenation saturation of the nerve innervation area and pinprick sensory tests at 5 min were assessed before the block and at 5-min intervals till 30 min after the block. |
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| L group | Patients scheduled for elective knee arthroscopy with peripheral nerve block will receive ultrasound-guided femoral nerve block with 0.25% ropivacaine. Regional tissue oxygenation saturation of the nerve innervation area and pinprick sensory tests were assessed at 5 min before the block and at 5-min intervals till 30 min after the block. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| tissue oxygenation saturation | Device | tissue oxygenation saturation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Regional tissue oxygenation saturation after successful femoral nerve block | rSO2 | at 5-minute intervals till 30 minutes after regional block |
| Measure | Description | Time Frame |
|---|---|---|
| Pinprick sensory scores | A 3-level scale was used to grade the intensity of sensory block using pinprick stimulation: 0=normal sensation; 1=analgesia; 2=anesthesia. | 5 minute before regional block and at 5-minute intervals till 30 minutes after regional block |
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Inclusion Criteria:
Exclusion Criteria:
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One hundred adult patients scheduled for elective knee arthroscopy with peripheral nerve block
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| Name | Affiliation | Role |
|---|---|---|
| Xiangdong Chen, Doctor | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Union Hospital | Wuhan | Hubei | China |
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