Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The biochemical differences in the composition of breast milk and formula have not been profoundly established in all compound groups. Increased understanding of breast milk composition, the normal variation of various bioactive compounds and their levels is required to be able to develop formulas better corresponding the breast milk, and ensure the optimal development of also the formula-fed babies.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Breast-feeding women | A single breast-milk sample will be collected from 20 women who breast-feed their child (0-6 months old). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Breast-milk | Other | A single breast-milk sample will be collected from 20 women. Milk samples will be pooled for analysis. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Relative proportions (%) of regioisomers within selected molecular species (acyl carbon number:number of double bonds 50:1 and 52:2) in triacylglycerols. | Isolation of lipids from the milk with solvent extraction. Isolation of triacylglycerols with solid phase extraction. Negative ionization of the triacylglycerols with ammonia. Selection of the molecular weight species in the first quadruple of the MS/MS. Fragmentation of the selected ions with argon. Separation of the fragment ions in the second quadrupole of the MS/MS. Calculation of the relative proportions of regioisomers with a computer software. | 11/2018-12/2019 |
| Relative proportions (%) of fatty acids in triacylglycerols of human milk. | Isolation of lipids from the milk with solvent extraction. Isolation of triacylglycerols with solid phase extraction. Quantitation with gas chromatograph coupled with flame ionization detector in relation to external standards. | 11/2018-12/2019 |
| Quantity (mg/ml) of lipid soluble compounds in triacylglycerols of human milk. | Isolation of lipids from the milk with solvent extraction. Gravimetric analysis of the lipids. | 11/2018-12/2019 |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Self-representation
18-45 years old women who breast-feed their 0-6 months old child
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Kaisa M Linderborg, PhD | University of Turku | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Biochemistry, University of Turku | Turku | 20014 | Finland |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D061186 | Breast Milk Expression |
| ID | Term |
|---|---|
| D001942 | Breast Feeding |
| D005247 | Feeding Behavior |
| D001519 | Behavior |
Not provided
Not provided
| ID | Term |
|---|---|
| D008892 | Milk |
| ID | Term |
|---|---|
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D003611 | Dairy Products |
Not provided
Not provided
Not provided
Not provided
Not provided
Human breast-milk samples
| D005502 |
| Food |
| D019602 | Food and Beverages |