Postoperative Complications Following Total Knee Arthroplasty

Comparison of Effects of Combined Spinoepidural and General Anesthesia Effects on Incidence of Postoperative Complications Following Total Knee Arthroplasty

The aim of this study is to investigate the effect of combined spinoepidural and general anesthesia on the incidence of postoperative complications following total knee arthroplasty

Total knee arthroplasty is known to cause complications (pulmonary thromboembolism, acute kidney injury, arryhthmias and infection). The investigators aimed to study the effects of two different anesthesia techniques, i.e. combined spinoepidural anesthesia and general anesthesia on the incidence of postoperative complications such as arrhythmia, pulmonary thrombeoembolism, infection, acute kidney injury and mortality.

Inclusion Criteria:

• Patients scheduled to undergo elective unilateral total knee arthroplasty

Exclusion Criteria:

• Patient refusal
• Scheduled for bilateral or unilateral unicondylar knee arthroplasty
• Known history of allergy to drugs used in the study
• Severe systemic disease
• Morbid obesity (BMI>30)
• History of renal dysfunction