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The effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels: the randomized controlled trial
Vitamin D structurally similar to steroids. Made from the skin. And metabolism of the liver, kidneys, vitamin D levels in the bloodstream are two types of vitamin D 2 (Ergocalciferol) and vitamin D 3 (Cholecalciferol) Vitamin D regulates calcium and phosphorus levels in the body. Including the accumulation of minerals in the bone. Vitamin D is important in the formation of bones and teeth and the normal growth of children, affects the reabsorption of amino acids in the kidneys, regulates the amount of calcium and phosphorus in the blood Vitamin D deficiency in pregnant affects the mother and baby example high maternal blood pressure during pregnancy, diabetes during pregnancy, increase birth body weight of baby. low calcium seizures Infants, baby have bones and growth disorders. Currently, no vitamin D supplement is used in pregnant women in Thailand who attend antenatal clinics. The researcher has proposed to study the effects of vitamin D supplement during pregnancy on postpartum maternal and fetal vitamin D levels by using vitamin D 20,000IU / week
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oral calciferol group | Experimental | Subjects will receive oral calciferol 20,000 iu per week during pregnancy until delivered |
|
| oral placebo group | Placebo Comparator | Subjects will receive oral placebo 1 tab per week during pregnancy until delivered |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Calciferol | Drug | calciferol capsule |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| effect of vitamin D 2 supplementation during pregnancy | To study the effect of vitamin D 2 supplementation during pregnancy on postpartum maternal and fetal vitamin D levels effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels | within 30 minute after delivered |
| Measure | Description | Time Frame |
|---|---|---|
| vitamin D levels in maternal blood during pregnancy | To assess vitamin D levels in maternal blood during pregnancy | at first time ANC |
| vitamin D levels in maternal blood after vitamin D supplementation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Patitta Vacharaprechaskul | Department of Medical Services Ministry of Public Health of Thailand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rajavithi hospital | Bangkok | Thailand | 10400 | Thailand |
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| ID | Term |
|---|---|
| D002762 | Cholecalciferol |
| ID | Term |
|---|---|
| D002782 | Cholestenes |
| D002776 | Cholestanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
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| Placebo | Drug | placebo capsule |
|
|
To assess vitamin D levels in maternal blood after vitamin D supplementation during pregnancy
| within 30 minute after delivered |
| D011083 |
| Polycyclic Compounds |
| D013261 | Sterols |
| D014807 | Vitamin D |
| D012632 | Secosteroids |
| D008563 | Membrane Lipids |
| D008055 | Lipids |