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use seseme oil and corticosteroid topically for two groups
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sesame oil in orabase | Experimental | 20 gm sesame oil-80 gm CMC 3 times per day for one month |
|
| triamcinolone in orabase | Active Comparator | 140 gm triamcinolone-50 gm Na CMC 3 times per day for one month |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sesame Oil | Drug | Sesame oil(80 gm NaCMC-20 gmSesame oil) |
|
| Measure | Description | Time Frame |
|---|---|---|
| pain intensit measure | measured by visual analogue scale where0 no pain and 10 sever pain | 4 weeks |
| reduction of clinical signs measure | Thongprasom Score 5 = white striae with erosive area = 1 cm2 Score 4 = white striae with erosive area < 1 cm2 Score 3 = white striae with erosive area > 1 cm2 Score 2 = white striae with atrophic area < 1 cm2 Score 1 = mild white striae only Score 0 = no lesion normal | 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Salivary level of oxidative stress biomarker (MDA) | measured by reaction with thiobarbituric acid (TBA) | 4 weeks |
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Inclusion Criteria:
Patients who will be clinically diagnosed as having atrophic &/or erosive oral lichen planus.
Exclusion Criteria:
Pregnant and lactating ladies.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mona Taha Mohammed Ahamed, Master | Contact | 01123294474 | mona.taha@dentistry.cu.edu.eg | |
| Amal ALI Ali, LEcturer | Contact | 01156520918 | amal.ali@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Mona Taha Mohammed Ahammed, MD | Cairo U | Principal Investigator |
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sesame oil in orabase(80 gm CMC -20 gm sesame oil)
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| triamcinolone in orabase | Drug | triamcinolone 140 gm-Na CMC 50 gm |
|
|
| ID | Term |
|---|---|
| D017676 | Lichen Planus, Oral |
| ID | Term |
|---|---|
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D008010 | Lichen Planus |
| D017512 | Lichenoid Eruptions |
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D012715 | Sesame Oil |
| D014221 | Triamcinolone |
| C056627 | Orabase |
| ID | Term |
|---|---|
| D004042 | Dietary Fats, Unsaturated |
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
| D005224 | Fats, Unsaturated |
| D010938 | Plant Oils |
| D009821 | Oils |
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D013259 | Steroids, Fluorinated |
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