The Effects of Hesperidin and Flaxseed in Prediabetes

Evaluation of the Effects of Hesperidin and Flaxseed Supplementation in Patients With Prediabetes

To study the effects of Hesperidin and flaxseed supplement in patients with prediabetes, 50 patients will be randomly allocated to control group or 2 capsules Hesperidin and 30 gram flaxseed for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, lipid profiles, blood pressure, blood sugar, inflammatory and anthropometric factors will be assessed and compared between groups.

Inclusion Criteria:

• Age of 18 to 70 years prediabetes: impaired fasting glucose (>100 mg/dL) and/or HbA1C 5.7% to 6.5%, and overweight or obese with body mass index range of 25 to 40 kg/m2

Exclusion Criteria:

• pregnancy or lactation
• A history of Cardiovascular disease, Pulmonary disease, Renal disease & Celiac disease; Cirrhosis
• Following program to lose weight in recent 3 mo