Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia

Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia

Four methods are routinely used to monitor CO2 in patients. End tidal CO2 (EtCO2) is monitored through the endotracheal tube during general anesthesia. CO2 is also monitored in other healthcare settings transcutaneously (TCO2), via finger stick capillary CO2 (CapCO2), and arterial blood gas (ABG). The purpose of this study is to perform all four measurements simultaneously during general anesthesia to identify which measure provides the most accurate data with the least amount of patient risk.

Inclusion Criteria:

• Have a confirmed diagnosis of cystic fibrosis (positive sweat chloride value ≥ 60 mEq/L) and/or genotype with two identifiable mutations consistent with CF, accompanied by one or more clinical features consistent with the CF phenotype)
• Hemodynamically stable undergoing general anesthesia for a scheduled procedure

Exclusion Criteria:

• Patients not diagnosed with CF
• CF patients undergoing anesthesia for emergency procedures