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Elderly patients generally have a tendency for having sarcopenia which refers to muscle loss that may be related to many factors. These patients also have a tendency to falls and injuries. Whether elderly sarcopenic patients have abrupt blood pressure drops upon standing remains unknown. Therefore, in this study, we sought to determine the incidence of orthostatic hypotension in sarcopenic elderly patients and compare it with elderly patients with no sarcopenia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elderly with sarcopenia | 50 patients aged 75 or older with sarcopenia Intervention: Each patient's supine and standing blood pressures will be measured. |
| |
| Elderly without sarcopenia | 50 patients aged 75 or older without sarcopenia Intervention: Each patient's supine and standing blood pressures will be measured. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| blood pressure measurement | Diagnostic Test | Intervention: Each patient's supine and standing blood pressure measurements will be recorded |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in blood pressure | All blood pressure measurements will be performed in the morning after an eight-hour fasting. After 5-minute rest, the first blood pressure measurement will be taken when the patients are supine. Later, three more consecutive measurements will be recorded when the patients stand up each being one-minute apart. All measurements will be performed using a fully automated sphygmomanometer that is attached with the correctly sized cuff matching to the patients' upper arm circumference. OH is defined as a decrease in systolic blood pressure of 20 mm Hg or a decrease in diastolic blood pressure of 10 mm Hg within 3 minutes of standing. The accompanying symptoms such as dizziness, unable to maintain balance, blurred vision will also be recorded. | 0-3 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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Elderly patients ( 75 or older) with and without sarcopenia
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kudret Keskin, MD | Contact | 0212 3735000 | 5188 | keskinkudret@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Kadriye Orta Kılıçkesmez, Prof | Şişli Hamidiye Etfal Education and Research Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Şişli Hamidiye Etfal Education and Research Hospital | Recruiting | Istanbul | 34200 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30039599 | Background | Hashimoto Y, Kaji A, Sakai R, Hamaguchi M, Okada H, Ushigome E, Asano M, Yamazaki M, Fukui M. Sarcopenia is associated with blood pressure variability in older patients with type 2 diabetes: A cross-sectional study of the KAMOGAWA-DM cohort study. Geriatr Gerontol Int. 2018 Sep;18(9):1345-1349. doi: 10.1111/ggi.13487. Epub 2018 Jul 24. |
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| ID | Term |
|---|---|
| D007024 | Hypotension, Orthostatic |
| D055948 | Sarcopenia |
| ID | Term |
|---|---|
| D054971 | Orthostatic Intolerance |
| D054969 | Primary Dysautonomias |
| D001342 | Autonomic Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D001795 | Blood Pressure Determination |
| ID | Term |
|---|---|
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D010808 | Physical Examination |
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| D007022 | Hypotension |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |