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| Name | Class |
|---|---|
| University of Birmingham | OTHER |
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The aim of this study is to characterise exogenous carbohydrate oxidation rates during exercise, when ingesting glucose (polymers) only, compared to glucose-fructose mixtures, and glucose-fructose mixtures ingested in hydrogel form.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fructose-maltodextrin ingestion | Active Comparator | Ingestion of fructose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak. |
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| Fructose-maltodextrin hydrogel ingestion | Experimental | Ingestion of fructose and maltodextrin (glucose polymers) encapsulated in alginate-pectin hydrogel, drinks at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak. |
|
| Glucose-maltodextrin ingestion | Active Comparator | Ingestion of glucose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fructose-maltodextrin | Dietary Supplement | Fructose plus maltodextrin in a ratio of 1:1.4, diluted in water to produce a 16% carbohydrate solution. |
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| Measure | Description | Time Frame |
|---|---|---|
| Peak exogenous carbohydrate oxidation rate | Peak exogenous carbohydrate oxidation rate during 120 min of treadmill running. Measured using isotope ratio mass spectrometry and reported in grams per minute | 120 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Total carbohydrate oxidation | Total carbohydrate oxidation during 120 min of treadmill running. Measured using indirect calorimetry and reported in grams. | 120 minutes |
| Ratings of gastrointestinal discomfort |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department for Health, University of Bath | Bath | BA2 7AY | United Kingdom |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| Fructose-maltodextrin hydrogel | Dietary Supplement | Fructose plus maltodextrin in a ratio of 1:1.4, encapsulated in an alginate-pectin hydrogel diluted in water to produce a 16% carbohydrate solution. |
|
| Glucose-maltodextrin | Dietary Supplement | Glucose plus maltodextrin in a ratio of 1:1.4, diluted in water to produce a 16% carbohydrate solution. |
|
Subjective ratings of gastrointestinal discomfort during 120 min of treadmill running. Measured using a 9-item questionnaire on a scale of 1 to 7, where 1 = No discomfort at all and 7 = very severe discomfort.
Items: Stomach; Heartburn; Acid reflux; Nausea; Rumbling; Bloated; Burping; Passing gas; Bowel movement.
| 120 minutes |
| Total fat oxidation | Total fat oxidation during 120 min of treadmill running. Measured using indirect calorimetry and reported in grams. | 120 minutes |
| Plasma insulin concentrations | Plasma insulin concentrations during 120 min of treadmill running. Measured using enzyme-linked immunosorbent assay and reported in pmol/L. | 120 minutes |
| Plasma glucose concentrations | Plasma lactate concentrations during 120 min of treadmill running. Measured using colourimetric assay and reported in mmol/L. | 120 minutes |
| Plasma lactate concentrations | Plasma lactate concentrations during 120 min of treadmill running. Measured using colourimetric assay and reported in mmol/L. | 120 minutes |
| Plasma non-esterified fatty acid concentrations | Plasma insulin concentrations during 120 min of treadmill running. Measured using colourimetric assay and reported in umol/L. | 120 minutes |
| Ratings of perceived exertion | Subjective ratings of perceived exertion using the Borg scale (1982) during 120 min of treadmill running. Measured on a scale of 6 to 20, where 6 = no exertion at all, and 20 = maximal exertion. | 120 minutes |
| Heart rate | Heart rate during treadmill running measured by telemetry and reported in beats per minute. | 120 minutes |
| Rate of oxygen consumption | Rate of oxygen consumption during 120 min of treadmill running. Measured using indirect calorimetry and reported in litres per minute. | 120 minutes |
| Rate of carbon dioxide production | Rate of carbon dioxide production during 120 min of treadmill running. Measured using indirect calorimetry and reported in litres per minute. | 120 minutes |