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The files of hemorrhagic obstetric patients undergoing surgery and followed in the intensive care unit and using Fibrinogen and blood products were included in the study between January 2015- September 2018 at the Anesthesiology and Reanimation Clinic of SBU Kanuni Sultan Süleyman Training and Research Hospital. Patients under 18 years of age were excluded from the study. In this study, ages, operation types, number of blood and products, the amount of fibrinogen, the results of the hemogram and bleeding parameters, the levels of fibrinogen, the duration of hospital stay and the intensive care unit were recorded.
Bleeding is an important event that threatens the patient's life. Too much blood and blood products can be used in massive bleeding. However, unwanted allergic reactions may occur in blood and blood product transfusions. Fibrinogen is the first coagulation factor in coagulopathy. Some studies have shown that when the fibrinogen level falls to <150-200 mg / dl, the bleeding increases dramatically.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fibrinogen and blood products | Other | Fibrinogen and blood products |
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of fibrinogen (mg/L) | Significant independent predictor for evolution to severe PPH was plasma fibrinogen level. | 24 hours |
| Measurement of hemoglobin (g/dL) | Postpartum hemorrhage (PPH) is a major contributor to maternal death and severe maternal morbidity | 24 hours |
| Amount of fibrinogen consantrates | in order to avoid PPH | 24 hours |
| Amount of blood products (unit) | degree of hemorrhagie | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Hospital stay days | for the recovery time of patients | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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obstetric patients
- Obstetric patients who underwent surgery and followed in ICU and Used Fibrinogen and Blood products in peroperatively or postoperatively
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| Name | Affiliation | Role |
|---|---|---|
| Ayca Sultan Sahin, MD | Kanuni Sultan Suleyman Education and Training Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kanuni Sultan Suleyman Education and Training Hospital | Istanbul | Kucukcekmece | 34306 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D006470 | Hemorrhage |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D005340 | Fibrinogen |
| ID | Term |
|---|---|
| D000209 | Acute-Phase Proteins |
| D001798 | Blood Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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| D001779 |
| Blood Coagulation Factors |
| D011498 | Protein Precursors |
| D001685 | Biological Factors |