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This multicenter, prospective randomized controlled study is designed to applicate perioperative Enhanced recovery after surgery (ERAS) management for children with acute complicated appendicitis, the aim is to promote postoperative recovery, shorten the hospital length of stay, and reduce the incidence of postoperative complications.
The purpose of this study is through multi-center prospective RCT research, to discuss the application of ERAS in children with acute complicated appendicitis, including its preoperative rehydration, postoperative analgesia, preoperative and postoperative antibiotics application, as well as the discharge standards and so on. The major outcome is whether it can reduce the length of stay in hospital (LOS), secondary outcomes are included the incidence of postoperative complications and postoperative readmission rate, etc.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ERAS group | Experimental | interventions: 1.preoperative pain control; 2.avoiding application of ureter; 3.avoiding application of gastric tube; 4.avoiding application of irrigation; 5.avoiding application of drainage; 6.early exercising postoperatively; 7.early oral feeding postoperatively; 8.early discharging. |
|
| control group | No Intervention | normal treatment |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ERAS | Combination Product |
|
| Measure | Description | Time Frame |
|---|---|---|
| length of stay | less hospital length of stay | through study completion, an average of 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| first time for postoperative feeding | earlier postoperative feeding | up to 72 hours |
| first time for postoperative exercising | earlier postoperative exercising |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jiexiong Feng, MD | Tongji Hospital, HUST, China | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tongji Hospital | Wuhan | Hubei | 430030 | China |
De-identified individual participant data for all primary and secondary outcome measures will be made available.
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| ID | Term |
|---|---|
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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|
| 1-2 days |
| rate of postoperative complication | less postoperative complication | 1 months |
| rate of re-operation | less rate of re-operation | 1 months |
| rate of re-admission | less rate of re-admission | 1 months |