Early Neurological Deterioration in Patients With Acute Ischemic Stroke

Explore the Causes and Predictors of Early Neurological Deterioration Occurred in Patients With Acute Ischemic Stroke

This study set out to explore the risk factors of early neurological deterioration (END) occurred in patients with acute ischemic stroke and to investigate the corresponding predictors.

END refers to the illness aggravation occurred in the early stage of stroke and often indicates a poor outcome. Some clinical scales may play an important role in its diagnoses and treatments. Across the reviewed studies, the risk factors of END, which included biochemical parameters, neuroimaging, ect. were explored incompletely and the effective predictors of END is unknown. We aimed to explore the risk factors of END and investigate the predictive value of certain scales.

Inclusion Criteria:

• Subjects with acute ischemic stroke
• Subjects with detailed progress notes

Exclusion Criteria:

• Subjects with thrombolysis therapy
• Subjects with transient ischemia attach
• Subjects complicated with seriously underlying diseases