China Health Big Data | NCT03699228

Studies
China Health Big Data

NCT03699228

Sponsor

Beijing Jishuitan Hospital

Status

Recruiting

Last Update Posted

Aug 17, 2025Actual

Enrollment

30,000Estimated

Phase

Not provided

Conditions

Osteoporosis
Obesity
Liver Steatoses

Interventions

Not provided

Countries

China

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Feb 2025

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Dec 1, 2017Actual

Primary Completion Date

Jun 30, 2026Estimated

Completion Date

Dec 31, 2026Estimated

First Submitted Date

Oct 5, 2018

First Submission Date that Met QC Criteria

Oct 5, 2018

First Posted Date

Oct 9, 2018Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Aug 13, 2025

Last Update Posted Date

Aug 17, 2025Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

xiaoguang Cheng, professor of radiology, chairman of department, Beijing Jishuitan HospitalPrincipal Investigator

Lead Sponsor

Beijing Jishuitan HospitalOTHER

Collaborators

Name	Class
Chinese PLA General Hospital	OTHER
Ruijin Hospital	OTHER
Huashan Hospital	OTHER
Henan Provincial People's Hospital

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

FDAAA801 Violation

Not provided

Description Module

Brief Summary

In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. The aim of this study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Detailed Description

Low dose Chest CT scan is the standard for lung cancer in the health check center in China. Quantitative computed tomography (QCT) is utilizing the CT raw data to measure the bone mineral density (BMD), the visceral fat (VAT) and liver fat content in human, which can be widely used in the diagnosis of osteoporosis, the assessment of obesity and liver steatosis. In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. This study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

30,000Estimated

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
The spinal volumetric bone mineral density (vBMD)	The volumetric bone mineral density of L1-2 measured by QCT	2 year

Secondary Outcomes

Measure	Description	Time Frame
The visceral adipose tissue (VAT)	The visceral adipose tissue (VAT) measured by quantitative computed tomography (QCT)	2 year
Liver fat	Liver fat measurement by quantitative computed tomography (QCT)

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

health check subjects 30-90 years old low dose chest CT scan

Exclusion Criteria:

pregnant women metal implant in the CT scan area

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

30 Years

Maximum Age

90 Years

Standard Ages

AdultOlder Adult

Study Population

General health check population

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
xiaoguang cheng, md	Contact	0086-010-58516947		xiao65@263.net
xiaoxia fu, md	Contact	0086-13683132746

Overall Officials

Name	Affiliation	Role
xiaoguang cheng, MD	Beijing Jishuitan Hospital	Principal Investigator
qiang zeng	General PLA hospital	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Wu Hu Yijishan Hospital	Recruiting	Wuhu	Anhui	100035	China

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
38267987	Derived	Sun Y, Qi X, Wang X, Lin X, Zhou Y, Du Y, Liu A, Lv X, Zhou J, Li Z, Wu X, Zou Z, Zhang M, Zhu J, Shang F, Li Y, Li H. Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study. Lipids Health Dis. 2024 Jan 24;23(1):27. doi: 10.1186/s12944-024-02023-1.
37865752

ID	Term
D010024	Osteoporosis
D009765	Obesity
D005234	Fatty Liver

ID	Term
D001851	Bone Diseases, Metabolic
D001847	Bone Diseases
D009140	Musculoskeletal Diseases
D008659	Metabolic Diseases