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This study is a retrospective analysis that uses abdominal CT scans, which were originally taken for other medical reasons, to estimate bone age. By applying advanced deep learning methods, the investigators aim to develop a tool that can evaluate bone health and detect early signs of osteoporosis without requiring additional scans or radiation. This approach may help doctors better understand bone aging, improve screening for bone weakness, and provide patients with more personalized information about their bone health.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Peking University People's Hospital cohort | No intervention | ||
| Shandong Cohort | No intervention | ||
| Canton Cohort | No intervention | ||
| Guizhou cohort | No intervention | ||
| Hunan Cohort | No intervention | ||
| Inner Mongolia Cohort | No intervention | ||
| Shaanxi Cohort | No intervention | ||
| Shandong Cohort2 | No intervention | ||
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| Measure | Description | Time Frame |
|---|---|---|
| Radiomics-Based Bone Age Prediction Model | Extraction of radiomics features from abdominal CT images of the proximal femur and development of a machine learning model to estimate biological bone age. The performance of the model will be evaluated by comparing predicted bone age with chronological age. | Retrospective analysis of CT scans acquired between Sep 01.2024 to Oct 01.2025 |
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Inclusion Criteria:
Exclusion Criteria:
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This retrospective study included about 3,000 adult participants (aged over 18 years) who underwent noncontrast abdominal CT scans that fully covered the proximal femur across multiple regions in China. Participants with poor image quality, prior hip surgery or internal fixation, bone tumors, severe hip deformities, or prior proximal femur fractures were excluded. All scans were performed for non-orthopedic indications. The study was approved by the Institutional Ethics Committee (approval number: 2024PHB388-001).
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| hanwen Cheng, M.D | Contact | 86-19541080926 | chenghanwen1998@126.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CT machine | Recruiting | Beijing | China |
Our Research has not been finished yet.
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| Other province Cohort |
No intervention |