Carbetocin Versus Syntometrine in Obese Women Undergoing Elective Cesarean

Carbetocin Versus Syntometrine for Prevention of Postpartum Hemorrhage in Obese Women Undergoing Elective Cesarean Delivery

to compare effectiveness and tolerability of carbetocin versus syntometrine in prevention of Postpartum hemorrhage after cesarean section

A double-blind randomized study conducted on 1200 obese pregnant subjected randomly either to single 100 μg IV dose of carbetocin (600 women) or combination of 5 IU oxytocin and 0.5 mg ergometrine (600 women) after fetal extraction and before placental removal.

Prevention of postpartum haemorrhage (PPH) after cesarean section (CS) had been evaluated by measurement of drop of Hemoglobin and hematocrit, incidence of PPH and number of subjects needed additional oxytocic

Inclusion Criteria:

• All participants are at 37 - 40 weeks of gestational age
• Noncomplicated pregnancy.
• obese women with BMI > 30.

Exclusion Criteria:

• Participants with placenta previa,
• coagulopathy,
• preeclamptic
• known sensitivity to carbetocin,oxytocin or methergine were excluded