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Verify the influence off vitamin D supplementation and a whole body vibration (WBV) protocol during 03 months in older patients chronic obstructive pulmonary disease
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vitamin D supplementation | Active Comparator |
| |
| Vitamin D placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D | Dietary Supplement | a dose once a week |
| |
| Measure | Description | Time Frame |
|---|---|---|
| serum inflammatory marker Interleukine-6 (IL-6) | changes in total serum values of interleukine 6 | before and immediately up to 12 weeks in WBV training. |
| serum inflammatory marker Interleukine-8 (IL-8) | changes in total serum values of interleukine 8 | before and immediately up to 12 weeks in WBV training. |
| serum inflammatory marker TNF-alpha ( and BDNF) | changes in total serum values of tumoral necrose factor alpha | before and immediately up to 12 weeks in WBV training. |
| serum inflammatory marker and brain derived neurotrophic factor (BDNF) | changes in total serum values of brain derived neurotrophic factor | before and immediately up to 12 weeks in WBV training. |
| Measure | Description | Time Frame |
|---|---|---|
| Peripheral strength | Changes in Peripheral muscle strength assessed by the hand dynamometer (device that assess strength) in values obtained from the mean of 03 maneuvers of isokinetic contraction, in centimeters of water | before and immediately up to 12 weeks in WBV training. |
| Body composition |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UFPE | Recife | Pernambuco | 50740-560 | Brazil |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| ID | Term |
|---|---|
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D012632 | Secosteroids |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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| whole body vibration (WBV) |
| Other |
03 months of WBV training three times per week |
|
Changes in electrical bioimpedance assessing lean mass in segmental areas and trunk |
| before and immediately up to 12 weeks in WBV training. |
| Respiratory strength | Changes in respiratory strength obtained from a manovacuometer, collecting the major value of 03 maneuvers of the maximal inspiration (vacuometer) to the maximal expiration pressures (manometer), with values obtained in centimeters of water | before and immediately up to 12 weeks in WBV training. |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |