Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Aging generates immune, muscular and functional changes. In the pre-frail elderly these changes may be increased and, therefore, preventive interventions are indicated to minimize the consequences of sarcopenia in this population. This study aims to evaluate the effects of a whole body vibration training associated with the training of inspiratory muscles on the inflammatory, muscular and body composition outcomes in pre-frail elderly women.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| WBV + IMT | Experimental | Whole body vibration training associated with respiratory muscle training (WBV + IMT) |
|
| WBV + IMTsham | Active Comparator | Whole body vibration training associated with respiratory muscle training sham (WBV + IMTsham) |
|
| WBVsham + IMTsham | Sham Comparator | Whole body vibration training sham associated with respiratory muscle training sham (WBVsham + IMTsham) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| WBV + IMT | Other | The whole body vibration training will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 02 to 04 mm.The inspiratory muscle training will be performed through a device that provides inspiratory resistance. |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory Muscle Strength and Resistance | Maximum Inspiratory and Expiratory Pressure will be evaluated through manovacuometer | Change from Baseline respiratory muscle strength and resistance at 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Thickness of the quadriceps muscle | Ultrasound will be used to assess the thickness of the quadriceps muscle according to the pre-established protocol. | Change from Baseline thickness of the quadriceps muscle at 3 months |
| Diaphragmatic thickness |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Federal University of Pernambuco | Recife | Pernambuco | Brazil |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| WBV + IMTsham | Other | The whole body vibration training will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 02 to 04 mm.The inspiratory muscle training sham will be performed through a device without inspiratory resistance. |
|
| WBVsham + IMTsham | Other | Whole body vibration training will be performed through a vibrating platform coupled to a device that generates non-therapeutic low frequency vibration. The simulation of inspiratory muscle training will be performed through a device with no inspiratory resistance. |
|
Ultrasound will to use to evaluate diaphragm thickness non-invasively in the zone of apposition during tidal breathing and with changes in lung volume.
| Change from Baseline diaphragmatic thickness at 3 months |
| Diaphragmatic mobility | During respiration to total lung capacity, measurement of the diaphragmatic excursion will be assessed by ultrasonography. | Change from Baseline diaphragmatic mobility at 3 months |
| Body Composition | Body composition will be evaluated through bioimpedance balance | Change from Baseline body composition at 3 months |
| Inflammatory markers | Blood concentration of Interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha) and brain-derived neurotrophic factor (BDNF) will be assessed through blood plasma sample. | Change from Baseline inflammatory markers at 3 months |