Sleep Infra-slow Oscillations III

Sleep Infra-slow Oscillations III: an Observational Study in Healthy Subjects and Patients With Sleep Disorders With and Without Closed-loop Stimulation During Sleep

In young healthy subjects, we will apply sensory stimuli at specific times during sleep to evaluate the probability that the stimulus evokes an arousal.

Inclusion Criteria:

• Willingness to participate and written informed consent
• Aged 20 to 40 years at the time of screening
• Body mass index (BMI) ≤ 30

Exclusion Criteria:

• Pregnancy or breast feeding at the time of screening
• Sleep related breathing disorders
• Any other sleep related breathing disorder according to AASM criteria
• Current history of psychiatric disorders according to DSM-V
• Current chronic treatment that may affect sleep
• Any significant neurological disorder or other medical disease that may affect sleep
• Any unstable medical condition
• Any clinically significant sleep disorder