Due to the health crisis triggered by the COVID-19 pandemic and the consequent sanitary-organizational arrangements set up for its contrast it was necessary to interrupt the study before reaching the established sample size.

This study is designed to better understand the effect of Kinesio Taping applied using the Neurotaping technique on patients who underwent total knee arthroplasty surgery. Patients will be randomized in two groups: in the first group patients will follow a protocol of usual rehabilitation, while the second group will do the same but add the Kinesio Taping application. Main outcome will be the effect on edema, secondary outcome the effect on functionality after 13 days post surgery.

Inclusion Criteria:

• Program of total knee replacement;
• Signing and accepting informed consent.

Exclusion Criteria:

• pre-operative Barthel Index score < 70;
• program of revision of total knee replacement;
• grade III-IV heart failure;
• grade III-IV kidney failure;
• hypersensitive skin or intolerance to taping;
• Active cutaneous infection or open skin lesion on the sites of taping positioning;
• Body Mass Index > 34,9;
• Pregnant women;
• Not accepting informed consent;
• Impossibility to follow usual rehabilitation treatment.

Randomization list has been already generated but will not be available to the recruiters to avoid allocation bias.

Statistician that will handle the data analysis will not know which group is the interventional and which group is the control.

We were not able to mask the using of tape to the patients or the investigators because it is an evident treatment.