The aim of this study was to examine the efficacy of Kinesiotaping (KT) within postoperative rehabilitation after Total Knee Replacement (TKR) surgery by determining whether KT enhances early postoperative outcomes, in terms of reduction of swelling, pain relief and improvement in the function of the knee joint, compared to conventional rehabilitation without the use of KT.

Kinesiotaping and Rehabilitation after Total Knee Replacement The effectiveness of Kinesiotaping (KT) in postoperative rehabilitation remains scientifically unproven, despite its widespread use. KT is believed to reduce pain and swelling, improve muscle function, and enhance joint mobility by promoting blood flow and lymphatic drainage. However, high-quality studies assessing its efficacy, particularly following Total Knee Replacement (TKR), are lacking.

Aim of the Study The aim of this study is to demonstrate that KT, when applied during inpatient rehabilitation after TKR, improves clinical outcomes compared to standard rehabilitation without KT.

Specifically, the investigators aim to show that:

KT reduces postoperative swelling and pain, thereby enhancing knee function. KT promotes faster recovery of muscle strength and range of motion. KT shortens the time needed to achieve key postoperative milestones, allowing for a more effective rehabilitation process.

Inclusion Criteria:

• Adults aged ≥18 years.
• Patients who have undergone primary Total Knee Replacement (TKR) with uncomplicated wound conditions.
• No signs of infection post-surgery.
• Ability to understand study procedures and complete required questionnaires.

Exclusion Criteria:

• Revision TKR surgeries.
• Early postoperative complications (e.g., wound healing disorders, deep infections, thrombosis).
• Severe comorbidities (e.g., heart failure NYHA class 3-4, renal insufficiency grade 3-4, chronic lymphedema, dermatological conditions).
• Known allergies to Kinesiotaping (KT) or adhesive materials.
• Neurological or neuromuscular disorders.
• Cognitive impairments (e.g., dementia) affecting compliance.

We plan to share de-identified individual participant data that underlie the results reported in the publication, including data on primary and secondary outcomes (e.g., pain levels, knee circumference, range of motion, functional tests). Access to data will be available upon reasonable request to researchers conducting relevant studies. Data will be shared following publication and will be accessible for up to 5 years. Researchers must submit a formal proposal, and data sharing agreements will be required to protect privacy and confidentiality.