The present study aims at refining the understanding of the effect of pregnancy on breast cancer outcomes in the specific population of BRCA mutated patients with known history of breast cancer.

Inclusion Criteria:

• Diagnosis of invasive breast cancer between January 2000 and December 2020;
• Breast cancer diagnosis at the age of ≤ 40 years;
• Known presence of germline BRCA mutation.

Exclusion Criteria:

• Known BRCA mutation with no diagnosis of invasive breast cancer;
• Diagnosis of ovarian cancer or other malignancies with no history of invasive breast cancer;
• Diagnosis of hereditary or familiar invasive breast cancer without BRCA mutation or with BRCA genes not tested;
• Diagnosis of invasive breast cancer with germline BRCA variants of unknown significance.

Women only

Patients with diagnosis of invasive breast cancer between January 2000 and December 2020 at the age of ≤ 40 years and with known presence of germline BRCA mutation.

Undecided