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| ID | Type | Description | Link |
|---|---|---|---|
| 2017-A03144-49 | Other Identifier | ANSM |
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departure of the principal recruiter in the study
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The investigators hypothesize that trans-thoracic ultrasound performed by non-specialist gastroenterologists with a standard training by intensive care doctors will give equivalent results to those achieved by experts for a simple evaluation of hemodynamic status.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with liver cirrhosis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Trans-thoracic ultrasound | Other | Trans-thoracic ultrasound performed by an expert and a non-expert |
|
| Measure | Description | Time Frame |
|---|---|---|
| Concordance in Left Ventricular Ejection Fraction measurement on trans-thoracic ultrasound by expert versus a non-specialist gastroenterologist with standard training | Difference in measured Left Ventricular Ejection Fraction (%) | 48 hours |
| Concordance in E' wave at the lateral mitral ring and mitral E wave measurement by expert versus a non-specialist gastroenterologist with standard training | Difference in measured E / E' ratio | 48 hours |
| Concordance in stroke volume measurement by expert versus a non-specialist gastroenterologist with standard training | Difference in measured velocity-time integral (cm) | 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Death rate | Day 28 | |
| Duration of hospitalization | End of follow-up (maximum 28 days) | |
| Number of admissions to intensive care |
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Inclusion Criteria:
Exclusion Criteria:
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Cirrhosis patients admitted to the gastroenterology service for odematous-ascitic decompensation defined by edema of the lower limbs, and/or ascites, anasarca, associated or not with weight gain.
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| Name | Affiliation | Role |
|---|---|---|
| Jean François Bourgaux | CHU Nimes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Nimes | Nîmes | 30029 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36840793 | Result | Prost A, Bourgaux JF, Louart B, Caillo L, Daurat A, Lefrant JY, Pouderoux P, Muller L, Roger C. Echocardiographic hemodynamic assessment in decompensated cirrhosis: comparison between Intensivists and Gastroenterologists. J Clin Monit Comput. 2023 Oct;37(5):1219-1228. doi: 10.1007/s10877-023-00983-w. Epub 2023 Feb 25. |
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| End of follow-up (maximum 28 days) |
| Consummation of diuretics | Day 0 |
| albumin infusion necessity | Day 0 |
| Use of vasopressors | Day 0 |
| auto ejection fraction measurement on trans-thoracic ultrasound by expert | Doppler | Day 0 |
| lateral mitral annulus measurement on trans-thoracic ultrasound by expert | Doppler | Day 0 |
| Mitral E wave measurement on trans-thoracic ultrasound by expert | Doppler | Day 0 |
| Mitral A wave measurement on trans-thoracic ultrasound by expert | Doppler | Day 0 |
| Inferior vena cava collapsibility index measurement on trans-thoracic ultrasound by expert | Doppler | Day 0 |
| Presence of intrapulmonary shunt | Y/N | Day 0 |
| Presence of aortic stenosis | Y/N | Day 0 |
| Presence of mitral insufficiency | Y/N | Day 0 |
| Presence of mitral stenosis | Y/N | Day 0 |
| left atrium surface area | cm2 | Day 0 |
| left ventricle diameter | mm | Day 0 |
| Septal wall thickness | mm | Day 0 |
| Posterior wall thickness | mm | Day 0 |
| tricuspid annular plane systolic excursion | mm | Day 0 |
| tricuspid annular plane systolic velocity | cm/s | Day 0 |
| heart chamber dilation | Day 0 |
| pulmonary arterial hypertension | mmHg | Day 0 |
| Pericardial effusion | Day 0 |