Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Post-operative cognitive dysfunction is a common disease in patient undergoing general anaesthesia, especially in older patients. No correlations have been yet studied between intraoperative hypothermia and incidence of Delayed Neurocognitive Recovery. Investigators are going to estimate the Relative Risk of Hypothermia and emergence of Post-operative cognitive dysfunction in cardiac-surgery patients.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hearth-valve surgery |
| ||
| Hearth bypass surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hypothermia during Extracorporeal Circulation | Procedure | Normothermia during Extracorporeal Circulation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of Delayed Neurocognitive Recovery in Cardiac-Surgery | Discover changes between pre-operative general cognition tests (Montreal Cognitive Assessment and Short Portable Mental Status Questionnaire) test score and post-operative Montreal Cognitive Assessment test score. | Patients will be subjected to Montreal Cognitive Assessment and Short Portable Mental Status Questionnaire test one day before surgery and 4-6 days after surgery |
| Incidence of Delayed Neurocognitive Recovery in Cardiac-Surgery | Discover changes between pre-operative Trail Making Test A and B score and post-operative Trail Making Test A and B score. | Patients will be subjected to Trail Making Test A and B one day before surgery and 4-6 days after surgery |
| Incidence of Delayed Neurocognitive Recovery in Cardiac-Surgery | Discover changes between pre-operative Digit Span Test score and post-operative Digit Span Test score. | Patients will be subjected to Digit Span Test one day before surgery and 4-6 days after surgery |
| Incidence of Delayed Neurocognitive Recovery in Cardiac-Surgery | Discover changes between pre-operative Frontal Assessment Battery test score and post-operative Frontal Assessment Battery test score and | Patients will be subjected to Frontal Assessment Battery test one day before surgery and 4-6 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Effects of hypothermia during Extracorporeal Circulation in Cardiac Surgery | Discover statistical significance difference in incidence of Post-Operative Cognitive Decline between patients undergoing normothermia and patients undergoing hypothermia during Extracorporeal Circulation in Cardiac Surgery | One day before surgery and 4-6 days after surgery patients will be subjected to cognitive test to diagnosticate Post-Operative Cognitive Decline |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Prospective Observational Case-Control
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Università degli Studi di Padova | Padova | PD | 35128 | Italy |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| D000071257 | Emergence Delirium |
| D007035 | Hypothermia |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D003693 | Delirium |
| D003221 | Confusion |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D001832 | Body Temperature Changes |
Not provided
Not provided