Normothermia Versus Hypothermia for Valvular Surgery Patients

Normothermia Versus Hypothermia for Patients With Valvular Heart Disease Operated Under Cardiopulmonary Bypass.

Cardiopulmonary bypass (CPB) has been used successfully for cardiac surgery for over half a century. Hypothermia became a ubiquitous practice for adult patients undergoing CPB. To date, most studies have been conducted in coronary artery bypass graft (CABG) patients with conflicting results. Current evidence does not support one temperature management strategy for all patients. The purpose of this study is to compare the efficiency and safety of normothermic versus hypothermic CPB in valvular surgery patients.

Inclusion Criteria:

• Isolated heart valve surgery
• Heart valve surgery plus CABG
• Age 20-80

Exclusion Criteria:

• urgent operation
• Left ventricle ejection fraction < 35%
• Decompensated congestive heart failure
• Chronic renal failure (glomerular filtration rate < 60 ml/min)
• Severe hepatic and pulmonary disease
• Bleeding diathesis or history of coagulopathy
• Planed deep hypothermic circulatory arrest
• History of acute myocardial infarction in the last 3 month
• Preoperative core temperature >37oC