Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. The main outcomes are iris blood flow density and vascular density.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal Population | Normal population with different gender, different age different, different blood pressure, different ocular pressure, etc. All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. | ||
| Patients with common ophthalmic diseases | (1) conjunctivitis; (2) glaucoma; (3) childhood myopia; (4) uveitis; (5) diabetic retinopathy; (6) retinal detachment; (7) fundus neovascularization. All patients will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. | ||
| Patients using eye drops | (1) conjunctivitis patients treated with levofloxacin antibiotics; (2) glaucoma patients treated with prostaglandins, adrenaline or receptor blockers drugs; (3) childhood myopia patients treated with atropine drugs; (4) uveitis patients treated with hormones treatment. (5) diabetic retinopathy patients treated with vasodilator. All patients will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens before and after eyedrops. |
| |
| Ocular surgery patients | (1) cataract, phacoemulsification + intraocular lens implantation; (2) glaucoma, iridectomy; (3) fundus neovascularization, intraocular injection of anti-VEGF; (4) diabetic retinopathy, vitrectomy. All patients will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens before and after surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| OCTA (ZEISS) | Diagnostic Test | All participants will underwent imaging using the OCTA system (Zeiss) with the anterior segment optical adaptor lens. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Iris Vessel Geometric Characteristics | Iris vascular density and neovascular density | 0:00 8:00 14:00 20:00 |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Residents of Shanghai and patients from Shanghai Eye Hospital will be selected.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38308203 | Derived | Cui L, Xiao Y, Xiang Z, Chen Z, Yang C, Zou H. Study on the correlation between iris blood flow, iris thickness and pupil diameter in the resting state and after pharmacological mydriasis in patients with diabetes mellitus. BMC Ophthalmol. 2024 Feb 2;24(1):52. doi: 10.1186/s12886-024-03322-y. | |
| 34781913 | Derived |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003231 | Conjunctivitis |
| D005901 | Glaucoma |
| D009216 | Myopia |
| D003930 | Diabetic Retinopathy |
| D012163 | Retinal Detachment |
| D015861 | Retinal Neovascularization |
| D014605 | Uveitis |
| ID | Term |
|---|---|
| D003229 | Conjunctival Diseases |
| D005128 | Eye Diseases |
| D009798 | Ocular Hypertension |
| D012030 | Refractive Errors |
Not provided
Not provided
Not provided
Not provided
Not provided
| Jia Y, Xue W, Tong X, Wang Y, Cui L, Zou H. Quantitative analysis and clinical application of iris circulation in ischemic retinal disease. BMC Ophthalmol. 2021 Nov 15;21(1):393. doi: 10.1186/s12886-021-02165-1. |
| D012164 |
| Retinal Diseases |
| D003925 | Diabetic Angiopathies |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D048909 | Diabetes Complications |
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |
| D009389 | Neovascularization, Pathologic |
| D008679 | Metaplasia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014603 | Uveal Diseases |