Fat Grafting in Skin-grafted Deep Burn Scars

Fat Grafting in Immature Skin-grafted Burn Scars: a Randomised Controlled Clinical Trial

fat grafting in human skin-grafted immature burn scars histological, clinical and photographic follow-up

Objective: A randomised clinical trial was performed to determine the effect of autologous fat grafting on scar formation in early skin-grafted deep burn wounds.

Methods: Included patients received split-thickness skin grafting procedures for deep burn wounds less than 3 months ago. A homogenous scar area in each patient was divided into two equal parts. One part was treated with transcutaneous sharp needle autologous fat grafting, the adjacent part with transcutaneous saline injection as control. Results were evaluated by clinical assessment with scar scale questionnaires, histological examination, and objective scar assessment with Cutometer, Mexameter, Tewameter and Corneometer.

Inclusion Criteria:

• early skin-grafted deep burn scars
• otherwise healthy

Exclusion Criteria:

• concomitant disease