A Clinical Study of the Effects of Modified BII+Braun on Quality of Life After for Distal Gastric Cancer

A Single-center, Randomized, Controlled Clinical Study of the Effects of Modified and Traditional BII+Braun Digestive Tract Reconstruction Methods on Quality of Life After Radical Gastrectomy for Distal Gastric Cancer

The jejunum of the input segment is properly ligated with double line 7 at 3-5cm from the anastomotic site, and the jejunum of the output segment is extended to 30cm

The T1-4a N0-3 M0 gastric adenocarcinoma patients were used to evaluate whether the quality of life after modified BII+Braun digestive tract reconstruction was superior to the traditional BII+Braun digestive tract reconstruction

Inclusion Criteria:

• 18<age<75
• Gastric lesions were diagnosed as gastric adenocarcinoma by endoscopic biopsy
• The preoperative clinical stage is T1-4a,N0-3,M0(According to AJCC- 7th TNM tumor stage)
• It is expected that the results of R0 surgery can be obtained by performing distal gastrectomy and D2 lymph node dissection
• Preoperative ECOG performance status score 0/1
• Nutrition risk screening（NRS2002）
• Preoperative ASA score I-III
• Patient informed consent

Exclusion Criteria:

• Pregnancy or breastfeeding women
• Severe mental illness
• History of upper abdominal surgery
• History of gastric surgery (including ESD/EMR for gastric cancer)
• 3 years of history of other malignant diseases；
• Gastric cancer patients who have undergone neoadjuvant treatment or recommend neoadjuvant treatment
• A history of unstable angina or myocardial infarction within 6 months
• History of cerebral infarction or cerebral hemorrhage within 6 months
• There is a history of sustained systemic corticosteroid treatment within 1 month
• Needs simultaneous surgical treatment of other diseases；
• Gastric cancer complications (bleeding, perforation, obstruction) require emergency surgery
• Pulmonary function test FEV<1 predicted value 50%