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| Name | Class |
|---|---|
| Federal University of Rio Grande do Sul | OTHER |
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The main purpose of the present study was to evaluate the effect of a power training session on office and 24h ambulatory blood pressure in older adults with hypertension. As secondary outcomes, the investigators compared post-exercise hypotension, BP variability, and endothelial function between older men and women with hypertension.
The working hypothesis was that a single bout of power exercise would decrease both office and 24 h BP in comparison to a non-exercising control session and men and women would respond differently after a power training session.
Participants randomly performed two experimental sessions: power exercise training (PT) and non-exercising control at seated rest (Con). They maintained their current antihypertensive medications throughout the trial. Each session was composed of 20 min of rest in the supine position, 40 min of PT or Con protocols, and 60 min of rest in supine position after protocols. The PT was composed of 3 sets of 8-10 repetitions of 5 exercises performed in the following order: leg press, bench press, knee extension, upright row, and knee flexion, using an intensity corresponding to 50 % of 1-RM and two-minute intervals between sets and exercises. The concentric phase of exercises during each repetition was performed "as fast as possible" while the eccentric phase lasted 1-2 seconds. During the Con, the participants remained seated rest on the same exercise machines, but without any exercise. Standardized office BP was performed before and during the first hour (in intervals of 15 min) after exercise and control sessions. Together with the office BP evaluation in the pre and post sessions, the endothelium-dependent brachial vascular function was evaluated using Flow-mediated dilation. Afterwards, participants underwent 24h ambulatory BP monitoring..
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control session | No Intervention | Control session without any exercise. The participants remained in seated rest throughout 40 min | |
| Power Training Session | Experimental | The power training session lasted 40 min, in which the participants performed a resistance exercise session using high velocity contractions during the exercises characterizing a power training session |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Power Training Session | Behavioral | 3 sets of 8-10 repetitions of 5 exercises performed in the following order: leg press, bench press, knee extension, upright row, and knee flexion, using an intensity corresponding to 50 % of 1-RM and two-minute intervals between sets and exercises. The concentric phase of exercises during each repetition was performed "as fast as possible" while the eccentric phase lasted 1-2 seconds. |
| Measure | Description | Time Frame |
|---|---|---|
| Ambulatory Blood Pressure Monitoring | Mean 24-h, day-time, night-time of blood pressure in mmHg will be assessed after each experimental session (power training session and control session) | 24 hours after control and power training exercise session |
| Measure | Description | Time Frame |
|---|---|---|
| Office Systolic Blood Pressure | Systolic blood pressure in mmHg will be measured using automatic oscillometric before and after each experimental session throughout one hour | 60 minutes after control and power training exercise session |
| Office Diastolic Blood Pressure |
| Measure | Description | Time Frame |
|---|---|---|
| Sex Differences in Ambulatory Blood Pressure Monitoring, Office Blood Pressure, Endothelial Function and Blood Pressure Variability | 60 minutes and 24 hours after control and power training exercise session |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rodrigo Ferrari, PhD | Federal University of Rio Grande do Sul | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital de Clinicas de Porto Alegre | Porto Alegre | Rio Grande do Sul | 90035-903 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34335289 | Derived | de Oliveira Carpes L, Domingues LB, Schimitt R, Fuchs SC, Alhalimi T, Tanaka H, Ferrari R. Sex Differences in Post-exercise Hypotension, Ambulatory Blood Pressure Variability, and Endothelial Function After a Power Training Session in Older Adults. Front Physiol. 2021 Jul 16;12:657373. doi: 10.3389/fphys.2021.657373. eCollection 2021. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001519 | Behavior |
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A randomized controlled clinical trial with crossover design was performed in order to evaluate the effect of a power training session on office and 24h ambulatory blood pressure in older adults with hypertension.
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The randomization list was generated by an epidemiologist using a computer software. This epidemiologist did not participate in the recruitment or assignment to the experimental sessions. Participants and the research team were blinded to the randomization list until the moment of assignment.
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Diastolic blood pressure in mmHg will be measured using automatic oscillometric before and after each experimental session throughout one hour |
| 60 minutes after control and power training exercise session |
| Endothelial Function | Flow-mediated dilatation (FMD) assessed through high resolution ultrasonography before and after each experimental session throughout one hour | 60 minutes after control and power training exercise session |
| Blood Pressure Variability | Systolic and diastolic BP values obtained in the 24-hour ambulatory blood pressure monitoring, with valid measures included in a programmed software to calculate the average real variability of these measures. | 24 hours after control and power training exercise session |