Peripheral Parenteral Nutrition vs Conventional Fluid in Colorectal Resection in ERAS

A RANDOMIZED, CONTROLLED, CLINICAL TRIAL TO COMPARE PERIPHERAL PARENTERAL NUTRITION (PeriOlimel N4-E) VERSUS CONVENTIONAL FLUID THERAPY IN ENHANCED RECOVERY AFTER SURGERY (ERAS) PROTOCOL IN COLORECTAL CANCER SURGERY.

Assess if administration of early nutrition support with Perioperative Peripheral Nutrition (PeriOliclimonel) N4-E) in patients undergoing colon cancer resection in an Enhanced Recovery After Surgery (ERAS) Protocol improve the results of morbi-mortality and hospitalization versus standard intravenous fluid therapy.

The main objective is to determine if perioperative nutritional support with PeriOlimel N4-E, that reaches nutritional requirements of ERAS protocol for colorectal cancer surgery patients, can improve nutritional status so it decreases postoperative complications, hospital length of stay and costs, compared to conventional fluid therapy administration since patients receive oral nutrition at day 3-5.

Inclusion Criteria:

• scheduled colorectal cancer surgery
• ASA I-IV

Exclusion Criteria:

• Emergency surgery
• Distant metastasis
• Patient´s refusal to participate
• Allergy or hypersensitivity to egg or soy protein
• Advanced kidney or hepatic impairment
• Severe bleeding disorders
• Congenital abnormalities of amino acid metabolism
• Hyperlipidemia and severe or difficult to control hyperglycemia