Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| BASF | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to investigate the effects of EPA- and DHA-enriched omega-3 polyunsaturated fatty acid dietary supplements on overnight verbal and visual memory consolidation as well as morning alertness before and after 26 weeks of supplementation
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Olive oil Placebo | Placebo Comparator | 3 x 1 g capsules daily Placebo: olive oil |
|
| EPA-rich | Active Comparator | 3 x 1 g capsules daily containing a SMEDDS formulation of an EPA-enriched oil totalling 900 mg EPA and 360 mg of DHA |
|
| DHA-Rich | Active Comparator | 3 x 1 g capsules daily containing a SMEDDS formulation of an DHA-enriched oil totalling 900 mg DHA and 270 mg of EPA |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Olive Oil Placebo | Dietary Supplement | 6 months placebo supplementation |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Computerised Location Learning task | Delayed recall accuracy | 26 months |
| Verbal Learning task | Delayed recall accuracy | 26 months |
| Measure | Description | Time Frame |
|---|---|---|
| Computerised Location Learning task | Learning index | 26 months |
| Verbal Learning task | Learning index | 26 months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northumbria University | Newcastle upon Tyne | Tyne and Wear | NE1 8ST | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34113957 | Derived | Patan MJ, Kennedy DO, Husberg C, Hustvedt SO, Calder PC, Khan J, Forster J, Jackson PA. Supplementation with oil rich in eicosapentaenoic acid, but not in docosahexaenoic acid, improves global cognitive function in healthy, young adults: results from randomized controlled trials. Am J Clin Nutr. 2021 Sep 1;114(3):914-924. doi: 10.1093/ajcn/nqab174. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| EPA-rich |
| Dietary Supplement |
6 months placebo supplementation |
|
| DHA-rich | Dietary Supplement | 6 months placebo supplementation |
|
| Peg and Ball/Tower of London task | Planning time (ms) | pre, Mid and post dose measures |
| Peg and Ball/Tower of London task | Completion time (ms) | pre, Mid and post dose measures |
| Peg and Ball/Tower of London task | Errors (number) | pre, Mid and post dose measures |
| Simple reaction time task | reaction time speed from a simple reaction task | 26 months |
| Digit vigilance task | accuracy (%) | 26 months |
| Digit vigilance task | Reaction time (ms) | 26 months |
| Subjective Alertness | Subjective ratings of alertness upon waking on a visual analogue scale (0-100 with 100 denoting the most alert the participant has ever felt in their life) | 26 months |