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| Name | Class |
|---|---|
| Ginsana SA | OTHER |
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To date, only a small handful of studies have assessed the effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on cognitive function in healthy adults. The results from these studies are mixed, and have differed greatly in terms of methodology as regards sample size, treatment formulation and duration of the intervention. In order to address these issues, the present study aims to assess the effects of two different formulations of fish oil in parallel, and at doses consistent with the current recommended daily intake of oily fish, across a range of cognitive domains. The aim of the present investigation is therefore to specifically evaluate the effects of 12 weeks supplementation of DHA-rich fish oil and EPA-rich fish oil dietary supplements on cognitive function in healthy young adults maintaining a regular diet containing oily fish not more than once a week. Self-report mood assessments will form the secondary part of this investigation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DHA-rich fish oil | Active Comparator | 1 g DHA-rich fish oil containing 450 mg DHA + 90 mg EPA |
|
| EPA-rich fish oil | Active Comparator | 1 g EPA-rich fish oil containing 300 mg EPA + 200 mg DHA |
|
| Placebo | Placebo Comparator | 1 g Olive oil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| n-3 PUFAs | Dietary Supplement | 1 g DHA-rich fish oil taken daily for 12 weeks |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive performance | Performance is assessed using the COMPASS (Computerised Mental Performance Assessment) system, which presents a battery of standard cognitive tasks assessing aspects of attention, memory and executive function. The Cognitive Demand Battery (30 minutes)will also be administered and assesses cognitive performance under mental fatigue. | 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Mood | Mood will be evaluated using Bond-Lader VAS and the Depression, Anxiety and Stress Scales. | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Philippa A Jackson | Northumbria University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northumbria University | Newcastle upon Tyne | Tyne and Wear | NE1 8ST | United Kingdom |
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| Label | URL |
|---|---|
| Brain, Performance and Nutrition Research Centre, Northumbria University | View source |
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| Placebo |
| Dietary Supplement |
1 g olive oil taken daily for 12 weeks |
|
| n-3 PUFAs | Dietary Supplement | 1 g EPA-rich fish oil taken daily for 12 weeks |
|